Dietary Carbohydrates Could Lead to Osteoarthritis
WASHINGTON (Dispatches)-Researchers have found that carbohydrate composition of diets increased the risk of osteoarthritis in laboratory mice -- even when the animals didn't differ in weight.
In a study led by Oklahoma Medical Research Foundation, scientist Tim Griffin, Ph.D., researchers found that the carbohydrate composition of diets increased the risk of osteoarthritis in laboratory mice -- even when the animals didn't differ in weight.
Osteoarthritis, or OA, is the most common form of arthritis and the most widespread form of disability in the country, affecting nearly 27 million people in the U.S. It occurs when the cartilage that cushions bones in the joints breaks down and wears away, causing the bones to rub against one another.
Several factors can increase risk, including high-impact physical jobs, previous joint injuries, age and genetics, but carrying extra body weight is among the most proven contributors.
"Obesity is the one of the most significant factors for developing disease in the knee joint," said Oklahoma Medical Research Foundation scientist Tim Griffin, Ph.D.. "However, therapeutic strategies to prevent or treat obesity-associated OA are limited because of the uncertainly about the root cause of the disease."
Several factors can increase risk, including high-impact physical jobs, previous joint injuries, age and genetics, but carrying extra body weight is among the most proven contributors.
In a study led by Oklahoma Medical Research Foundation, scientist Tim Griffin, Ph.D., researchers found that the carbohydrate composition of diets increased the risk of osteoarthritis in laboratory mice -- even when the animals didn't differ in weight.
Osteoarthritis, or OA, is the most common form of arthritis and the most widespread form of disability in the country, affecting nearly 27 million people in the U.S. It occurs when the cartilage that cushions bones in the joints breaks down and wears away, causing the bones to rub against one another.
Several factors can increase risk, including high-impact physical jobs, previous joint injuries, age and genetics, but carrying extra body weight is among the most proven contributors.
"Obesity is the one of the most significant factors for developing disease in the knee joint," said Oklahoma Medical Research Foundation scientist Tim Griffin, Ph.D.. "However, therapeutic strategies to prevent or treat obesity-associated OA are limited because of the uncertainly about the root cause of the disease."
Several factors can increase risk, including high-impact physical jobs, previous joint injuries, age and genetics, but carrying extra body weight is among the most proven contributors.