Afghan officials said the attack targeted a convoy of militants in the Nazyan district on Saturday, also injuring one person and causing multiple casualties.
Meanwhile, local officials said militants launched an attack on security posts overnight, claiming that a local Taliban commander has been killed in a counter-attack by police forces.
The United States conducts drone strikes in Afghanistan and several other Muslim countries despite international criticism.
While Washington claims the targets of the drone attacks are al-Qaeda militants, local officials and witnesses have on many occasions maintained that civilians have been the victims of the attacks over the past few years.