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News ID: 79009
Publish Date : 27 May 2020 - 21:51

Researchers Discover Protein Inhibiting Cancer Development


COPENHAGEN (Dispatches) -- In a new study, researchers have discovered how the protein PP2A can inhibit tumor growth in mice. The protein turns off an enzyme that stimulates cell growth, thus inhibiting the development of cancer.
Proteins are found throughout our cells and regulate a lot of biological processes that are important forour survival. But some of them also regulate processes that can make us sick. Now, an international research team, with researchers from the University of Copenhagen at the forefront, has achieved a much better understanding of one such protein.
In a new study, the researchers discovered how the protein PP2A works at the molecular level, and how it inhibits the development of tumours in mice. The new results have been published in the scientific journal, the EMBO Journal.
‘We call PP2A a household protein because it is found almost everywhere. In everything living -- from simple yeast cells to complex cells in humans. PP2A removes phosphate groups on other proteins, and now we have found these proteins and how PP2A, via one of these proteins, inhibits cancer development’, says Jakob Nilsson, Professor at the Novo Nordisk Foundation Center for Protein Research.