"We will implement the blockade on imports of American goods in a directive,” Minister of Industry, Mine and Trade Muhammad Reza Nematzadeh said on Saturday.
The plan is in line with the "requirements” which Ayatollah Khamenei has notified President Hassan Rouhani of the need to empower national production, develop an "economy of resistance” and check imports of U.S.-made goods, he added.
The Leader wrote a letter more than a week ago to outline his conditional approval of the Joint Comprehensive Plan of Action (JCPOA) -- Iran’s nuclear accord reached in July with the U.S., Europe as well as Russia and China.
The letter demanded that the government take seriously the "economy of resistance", focusing on self-reliance instead of basing Iran's economy on external sources.
The Leader also instructed the government to guard against "unbridled imports" and check the entry of all goods from the United States when sanctions are lifted.
President Rouhani wrote back to Ayatollah Khamenei, assuring that his government would observe the Leader's guidance and considerations.
American products often find their way into the Iranian marketplace through back channels. There are other routes such as licensing workarounds and direct trade for goods not covered by U.S. sanctions which result in American products ending up in the Iranian market.
U.S. food and beverages such as Coca-Cola and Pepsi have local bottlers and distributors in Iran, but they say they have nothing to do with the American brands.
Earlier this month, U.S. media reports said Washington had approved exports of soft drinks to Iran, putting an end to a ban which had been in place since 1990s.
U.S. brands also make up the bulk of contraband cigarettes in Iran. Up to 6-7 billion Marlboro cigarettes, made by Philip Morris USA, are annually smoked in Iran which translates into imports of three truckloads per week, the ISNA news agency said in May.
A senior official said recently that Iran had launched a serious campaign to stem the flow of bootleg cigarettes.